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Ranolazine is an effective and remarkably safe agent for the treatment of patients with chronic stable angina, but its inhibition of voltage gated potassium channels and electrocardiogram (EKG) corrected QT (QTc) prolongation properties have lead many to question its safety when combined with antiarrhythmic drugs.


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Though many of those patients respond to other treatments, including surgery and other approved drugs, some still have angina despite such treatments.

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As with most of you, all of my cardiac enzymes, EKG and Echo all came back normal until I had my stress test.

Zyprexa (olanzapine), Seroquel (quetiapine), Geodon (ziprasidone HCl), and Lexapro (escitalopram) lost patent protection.

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